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A DOTA-peptide conjugate by copper-free click chemistry
Attachment of DOTA to a novel monofluoro-cyclooctyne facilitates bioconjugation to an azide-modified peptide via Cu-free click chemistry. The resulting conjugate was radiolabeled with (111)In to afford a potential targeted molecular imaging agent with high specific activity and in excellent radioche...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3774834/ https://ncbi.nlm.nih.gov/pubmed/20630750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.06.111 |
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