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The Pl(A2) polymorphism of integrin β(3) enhances outside-in signaling and adhesive functions
Genetic factors are believed to influence the development of arterial thromboses. Because integrin α(IIb)β(3) plays a crucial role in thrombus formation, we analyzed receptor adhesive properties using Chinese hamster ovary and human kidney embryonal 293 cells overexpressing the Pl(A1) or Pl(A2) poly...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC377456/ https://ncbi.nlm.nih.gov/pubmed/10727448 |
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