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Orai1 and Ca(2+)-independent phospholipase A(2) are required for store-operated I(cat-SOC) current, Ca(2+) entry, and proliferation of primary vascular smooth muscle cells

Store-operated Ca(2+) entry (SOCE) is important for multiple functions of vascular smooth muscle cells (SMC), which, depending of their phenotype, can resemble excitable and nonexcitable cells. Similar to nonexcitable cells, Orai1 was found to mediate Ca(2+)-selective (CRAC-like) current and SOCE in...

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Autori principali: Yang, Bo, Gwozdz, Tomasz, Dutko-Gwozdz, Joanna, Bolotina, Victoria M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774541/
https://ncbi.nlm.nih.gov/pubmed/22094335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00312.2011
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