S-acylation of Orai1 regulates store-operated Ca(2)(+) entry

Store-operated Ca(2+) entry is a central component of intracellular Ca(2+) signaling pathways. The Ca(2+) release-activated channel (CRAC) mediates store-operated Ca(2+) entry in many different cell types. The CRAC channel is composed of the plasma membrane (PM)-localized Orai1 channel and endoplasm...

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Dettagli Bibliografici
Pubblicato in:J Cell Sci
Autori principali: West, Savannah J., Kodakandla, Goutham, Wang, Qioachu, Tewari, Ritika, Zhu, Michael X., Boehning, Darren, Akimzhanov, Askar M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2021
Soggetti:
Short Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8255033/
https://ncbi.nlm.nih.gov/pubmed/34156466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.258579
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