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Chemically ubiquitylated histone H2B stimulates hDot1L-mediated intranucleosomal methylation

Numerous post-translational modifications of histones have been described in organisms ranging from yeast to humans(1). Growing evidence for dynamic regulation of these modifications, position- and modification-specific protein interactions, and biochemical crosstalk between modifications has streng...

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Autors principals: McGinty, Robert K., Kim, Jaehoon, Chatterjee, Champak, Roeder, Robert G., Muir, Tom W.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774535/
https://ncbi.nlm.nih.gov/pubmed/18449190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06906
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