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The n-SET Domain of Set1 Regulates H2B Ubiquitylation-Dependent H3K4 Methylation

Past studies have documented a cross-talk between H2B ubiquitylation (H2Bub) and H3K4 methylation, but little, if any, direct evidence exists explaining the mechanism underlying H2Bub-dependent H3K4 methylation on chromatin templates. Here, we took advantage of an in vitro histone methyltransferase...

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Hlavní autoři: Kim, Jaehoon, Kim, Jung-Ae, McGinty, Robert K., Nguyen, Uyen T. T., Muir, Tom W., Allis, C. David, Roeder, Robert G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615140/
https://ncbi.nlm.nih.gov/pubmed/23453808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.01.034
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