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Structure activity analysis of semisynthetic nucleosomes: Mechanistic insights into the stimulation of Dot1L by ubiquitylated histone H2B

Post-translational modification of histones plays an integral role in regulation of genomic expression through modulation of chromatin structure and function. Chemical preparations of histones bearing these modifications allows for comprehensive in vitro mechanistic investigation into their action t...

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Autores principales: McGinty, Robert K., Köhn, Maja, Chatterjee, Champak, Chiang, Kyle P., Pratt, Matthew R., Muir, Tom W.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785503/
https://ncbi.nlm.nih.gov/pubmed/19799466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb9002255
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