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Structure activity analysis of semisynthetic nucleosomes: Mechanistic insights into the stimulation of Dot1L by ubiquitylated histone H2B

Post-translational modification of histones plays an integral role in regulation of genomic expression through modulation of chromatin structure and function. Chemical preparations of histones bearing these modifications allows for comprehensive in vitro mechanistic investigation into their action t...

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Detalles Bibliográficos
Main Authors: McGinty, Robert K., Köhn, Maja, Chatterjee, Champak, Chiang, Kyle P., Pratt, Matthew R., Muir, Tom W.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785503/
https://ncbi.nlm.nih.gov/pubmed/19799466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb9002255
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