Histone H2B ubiquitylation disrupts local and higher order chromatin compaction

Regulation of chromatin structure involves histone post-translational modifications which can modulate intrinsic properties of the chromatin fiber to change the chromatin state. We used chemically defined nucleosome arrays to demonstrate that H2B ubiquitylation (uH2B), a modification associated with...

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Bibliographic Details
Main Authors: Fierz, Beat, Chatterjee, Champak, McGinty, Robert K., Bar-Dagan, Maya, Raleigh, Daniel P., Muir, Tom W.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078768/
https://ncbi.nlm.nih.gov/pubmed/21196936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.501
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