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Improved insulin-sensitivity in mice heterozygous for PPAR-γ deficiency
The thiazolidinedione class of insulin-sensitizing, antidiabetic drugs interacts with peroxisome proliferator–activated receptor γ (PPAR-γ). To gain insight into the role of this nuclear receptor in insulin resistance and diabetes, we conducted metabolic studies in the PPAR-γ gene knockout mouse mod...
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| Publicado en: | J Clin Invest |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2000
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC377448/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10675354/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI8538 |
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