Adipose-specific peroxisome proliferator-activated receptor γ knockout causes insulin resistance in fat and liver but not in muscle

Syndrome X, typified by obesity, insulin resistance (IR), dyslipidemia, and other metabolic abnormalities, is responsive to antidiabetic thiazolidinediones (TZDs). Peroxisome proliferator-activated receptor (PPAR) γ, a target of TZDs, is expressed abundantly in adipocytes, suggesting an important ro...

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Podrobná bibliografie

Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	He, Weimin, Barak, Yaacov, Hevener, Andrea, Olson, Peter, Liao, Debbie, Le, Jamie, Nelson, Michael, Ong, Estelita, Olefsky, Jerrold M., Evans, Ronald M.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 2003
Témata:	Biological Sciences
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307633/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14660788/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2536828100
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