Adipose-specific peroxisome proliferator-activated receptor γ knockout causes insulin resistance in fat and liver but not in muscle

Syndrome X, typified by obesity, insulin resistance (IR), dyslipidemia, and other metabolic abnormalities, is responsive to antidiabetic thiazolidinediones (TZDs). Peroxisome proliferator-activated receptor (PPAR) γ, a target of TZDs, is expressed abundantly in adipocytes, suggesting an important ro...

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Dettagli Bibliografici

Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	He, Weimin, Barak, Yaacov, Hevener, Andrea, Olson, Peter, Liao, Debbie, Le, Jamie, Nelson, Michael, Ong, Estelita, Olefsky, Jerrold M., Evans, Ronald M.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2003
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307633/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14660788/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2536828100
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