Adipose-specific peroxisome proliferator-activated receptor γ knockout causes insulin resistance in fat and liver but not in muscle

Syndrome X, typified by obesity, insulin resistance (IR), dyslipidemia, and other metabolic abnormalities, is responsive to antidiabetic thiazolidinediones (TZDs). Peroxisome proliferator-activated receptor (PPAR) γ, a target of TZDs, is expressed abundantly in adipocytes, suggesting an important ro...

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Détails bibliographiques
Auteurs principaux: He, Weimin, Barak, Yaacov, Hevener, Andrea, Olson, Peter, Liao, Debbie, Le, Jamie, Nelson, Michael, Ong, Estelita, Olefsky, Jerrold M., Evans, Ronald M.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2003
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC307633/
https://ncbi.nlm.nih.gov/pubmed/14660788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2536828100
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