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Xanthine oxidase contributes to mechanical ventilation-induced diaphragmatic oxidative stress and contractile dysfunction

Respiratory muscle weakness resulting from both diaphragmatic contractile dysfunction and atrophy has been hypothesized to contribute to the weaning difficulties associated with prolonged mechanical ventilation (MV). While it is clear that oxidative injury contributes to MV-induced diaphragmatic wea...

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Detalhes bibliográficos
Main Authors: Whidden, Melissa A., McClung, Joseph M., Falk, Darin J., Hudson, Matthew B., Smuder, Ashley J., Nelson, W. Bradley, Powers, Scott K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774324/
https://ncbi.nlm.nih.gov/pubmed/18974366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.91106.2008
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