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Mechanical ventilation induces diaphragmatic mitochondrial dysfunction and increased oxidant production

Mechanical ventilation (MV) is a life-saving intervention used in patients with acute respiratory failure. Unfortunately, prolonged MV results in diaphragmatic weakness, which is an important contributor to the failure to wean patients from MV. Our laboratory has previously shown that reactive oxyge...

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Detalhes bibliográficos
Main Authors: Kavazis, Andreas N., Talbert, Erin E., Smuder, Ashley J., Hudson, Matthew B., Nelson, W. Bradley, Powers, Scott K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906125/
https://ncbi.nlm.nih.gov/pubmed/19185055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2009.01.002
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