Mechanical Ventilation-Induced Oxidative Stress in the Diaphragm: Role of Heme Oxygenase-1

BACKGROUND: Prolonged mechanical ventilation (MV) results in a rapid onset of diaphragmatic atrophy that is primarily due to increased proteolysis. Although MV-induced protease activation can involve several factors, it is clear that oxidative stress is a required signal for protease activation in t...

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Detalhes bibliográficos
Main Authors: Falk, Darin J., Kavazis, Andreas N., Whidden, Melissa A., Smuder, Ashley J., McClung, Joseph M., Hudson, Matthew B., Powers, Scott K.
Formato: Artigo
Idioma:Inglês
Publicado em: American College of Chest Physicians 2011
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071271/
https://ncbi.nlm.nih.gov/pubmed/21106654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1378/chest.09-2787
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