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Leupeptin-based inhibitors do not improve the mdx phenotype
Calpain activation has been implicated in the disease pathology of Duchenne muscular dystrophy. Inhibition of calpain has been proposed as a promising therapeutic target, which could lessen the protein degradation and prevent progressive fibrosis. At the same time, there are conflicting reports as t...
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| Autores principales: | , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Physiological Society
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3774252/ https://ncbi.nlm.nih.gov/pubmed/20844259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00586.2009 |
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