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Leupeptin-based inhibitors do not improve the mdx phenotype

Calpain activation has been implicated in the disease pathology of Duchenne muscular dystrophy. Inhibition of calpain has been proposed as a promising therapeutic target, which could lessen the protein degradation and prevent progressive fibrosis. At the same time, there are conflicting reports as t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Selsby, Joshua, Pendrak, Klara, Zadel, Monica, Tian, Zuozhen, Pham, Jennifer, Carver, Ted, Acosta, Pedro, Barton, Elisabeth, Sweeney, H. Lee
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774252/
https://ncbi.nlm.nih.gov/pubmed/20844259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00586.2009
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