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Early apoptosis in different models of cardiac hypertrophy induced by high renin-angiotensin system activity involves CaMKII
The objective of this study was to establish whether 1) hyperactivity of renin-angiotensin-aldosterone system (RAAS) produces apoptosis in early stages of cardiac disease; and 2) Ca(2+)-calmodulin-dependent protein kinase II (CaMKII) is involved in these apoptotic events. Two models of hypertrophy w...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Physiological Society
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3774203/ https://ncbi.nlm.nih.gov/pubmed/22492934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.01383.2011 |
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