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Early apoptosis in different models of cardiac hypertrophy induced by high renin-angiotensin system activity involves CaMKII

The objective of this study was to establish whether 1) hyperactivity of renin-angiotensin-aldosterone system (RAAS) produces apoptosis in early stages of cardiac disease; and 2) Ca(2+)-calmodulin-dependent protein kinase II (CaMKII) is involved in these apoptotic events. Two models of hypertrophy w...

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Detalhes bibliográficos
Main Authors: Velez Rueda, J. Omar, Palomeque, Julieta, Mattiazzi, Alicia
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774203/
https://ncbi.nlm.nih.gov/pubmed/22492934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.01383.2011
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