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Relaxin Suppresses Atrial Fibrillation by Reversing Fibrosis and Myocyte Hypertrophy, and Increasing Conduction Velocity and Sodium Current in Spontaneously Hypertensive Rat Hearts
RATIONALE: Atrial fibrillation (AF) contributes significantly to morbidity and mortality in elderly and hypertensive patients and has been correlated to enhanced atrial fibrosis. Despite a lack of direct evidence that fibrosis causes AF, reversal of fibrosis is considered as a plausible therapy. OBJ...
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Glavni autori: | , , , , , , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
2013
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3774019/ https://ncbi.nlm.nih.gov/pubmed/23748429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.113.301646 |
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