Relaxin Suppresses Atrial Fibrillation in Aged Rats by reversing fibrosis and Upregulating Na(+)-Channels

BACKGROUND: Atrial fibrillation (AF) contributes significantly to morbidity and mortality in elderly patients and has been correlated with enhanced age-dependent atrial fibrosis. Reversal of atrial fibrosis has been proposed as therapeutic strategy to suppress AF. OBJECTIVE: To test the ability of r...

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Detalhes bibliográficos
Publicado no:Heart Rhythm
Main Authors: Henry, Brian, Gabris, Beth, Li, Qiao, Martin, Brian, Giannini, Marianna, Parikh, Ashish, Patel, Divyang, Haney, Jamie, Schwartzman, David, Shroff, Sanjeev G., Salama, Guy
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801709/
https://ncbi.nlm.nih.gov/pubmed/26711798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2015.12.030
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