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Modification of K(+) channel–drug interactions by ancillary subunits

Reconciling ion channel α-subunit expression with native ionic currents and their pharmacological sensitivity in target organs has proved difficult. In native tissue, many K(+) channel α-subunits co-assemble with ancillary subunits, which can profoundly affect physiological parameters including gati...

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Detalhes bibliográficos
Main Authors: Bett, Glenna C L, Rasmusson, Randall L
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375646/
https://ncbi.nlm.nih.gov/pubmed/18096604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.139279
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