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Modification of K(+) channel–drug interactions by ancillary subunits
Reconciling ion channel α-subunit expression with native ionic currents and their pharmacological sensitivity in target organs has proved difficult. In native tissue, many K(+) channel α-subunits co-assemble with ancillary subunits, which can profoundly affect physiological parameters including gati...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Science Inc
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2375646/ https://ncbi.nlm.nih.gov/pubmed/18096604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.139279 |
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