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Nox1 is over-expressed in human colon cancers and correlates with activating mutations in K-Ras
The NADPH-oxidase 1 (Nox1) is a homolog of gp91phox, the catalytic subunit of the phagocyte superoxide-generating NADPH-oxidase. Nox1 is expressed in normal colon epithelial cells and in colon tumor cell lines, and overexpression in model cells has been implicated in stimulation of mitogenesis and a...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3774003/ https://ncbi.nlm.nih.gov/pubmed/18398843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.23423 |
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