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Nox1 is over-expressed in human colon cancers and correlates with activating mutations in K-Ras

The NADPH-oxidase 1 (Nox1) is a homolog of gp91phox, the catalytic subunit of the phagocyte superoxide-generating NADPH-oxidase. Nox1 is expressed in normal colon epithelial cells and in colon tumor cell lines, and overexpression in model cells has been implicated in stimulation of mitogenesis and a...

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Bibliografiset tiedot
Päätekijät: Laurent, Eunice, McCoy, James W., Macina, Roberto A., Liu, Wenhui, Cheng, Guangjie, Robine, Sylvie, Papkoff, Jackie, Lambeth, J. David
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774003/
https://ncbi.nlm.nih.gov/pubmed/18398843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.23423
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