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NOS3 protects against systemic inflammation and myocardial dysfunction in murine polymicrobial sepsis

Nitric oxide (NO) has been implicated in the pathogenesis of septic shock. However, the role of NO synthase 3 (NOS3) during sepsis remains incompletely understood. Here, we examined impact of NOS3 deficiency on systemic inflammation and myocardial dysfunction during peritonitis-induced polymicrobial...

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Detalhes bibliográficos
Main Authors: Bougaki, Masahiko, Searles, Robert J., Kida, Kotaro, De Yu, Jia, Buys, Emmanuel S., Ichinose, Fumito
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774000/
https://ncbi.nlm.nih.gov/pubmed/19997049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e3181cdc327
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