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Mice lacking PGC-1β in adipose tissues reveal a dissociation between mitochondrial dysfunction and insulin resistance

Proper development and function of white adipose tissue (WAT), which are regulated by multiple transcription factors and coregulators, are crucial for glucose homeostasis. WAT is also the main target of thiazolidinediones, which are thought to exert their insulin-sensitizing effects by promoting mit...

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Bibliografiska uppgifter
Huvudupphovsmän: Enguix, Natàlia, Pardo, Rosario, González, Agustí, López, Víctor M., Simó, Rafael, Kralli, Anastasia, Villena, Josep A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773830/
https://ncbi.nlm.nih.gov/pubmed/24049736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2013.05.004
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