Mice lacking PGC-1β in adipose tissues reveal a dissociation between mitochondrial dysfunction and insulin resistance

Proper development and function of white adipose tissue (WAT), which are regulated by multiple transcription factors and coregulators, are crucial for glucose homeostasis. WAT is also the main target of thiazolidinediones, which are thought to exert their insulin-sensitizing effects by promoting mit...

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Главные авторы: Enguix, Natàlia, Pardo, Rosario, González, Agustí, López, Víctor M., Simó, Rafael, Kralli, Anastasia, Villena, Josep A.
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2013
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773830/
https://ncbi.nlm.nih.gov/pubmed/24049736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2013.05.004
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