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Mice lacking PGC-1β in adipose tissues reveal a dissociation between mitochondrial dysfunction and insulin resistance

Proper development and function of white adipose tissue (WAT), which are regulated by multiple transcription factors and coregulators, are crucial for glucose homeostasis. WAT is also the main target of thiazolidinediones, which are thought to exert their insulin-sensitizing effects by promoting mit...

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Bibliografiske detaljer
Main Authors: Enguix, Natàlia, Pardo, Rosario, González, Agustí, López, Víctor M., Simó, Rafael, Kralli, Anastasia, Villena, Josep A.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773830/
https://ncbi.nlm.nih.gov/pubmed/24049736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2013.05.004
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