ETV4 promotes metastasis in response to activation of PI3-kinase and Ras signaling in a mouse model of advanced prostate cancer

Combinatorial activation of PI3-kinase and RAS signaling occurs frequently in advanced prostate cancer and is associated with adverse patient outcome. We now report that the oncogenic Ets variant 4 (Etv4) promotes prostate cancer metastasis in response to coactivation of PI3-kinase and Ras signaling...

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Hlavní autoři: Aytes, Alvaro, Mitrofanova, Antonina, Kinkade, Carolyn Waugh, Lefebvre, Celine, Lei, Ming, Phelan, Vanessa, LeKaye, H. Carl, Koutcher, Jason A., Cardiff, Robert D., Califano, Andrea, Shen, Michael M., Abate-Shen, Cory
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
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PNAS Plus
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773788/
https://ncbi.nlm.nih.gov/pubmed/23918374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1303558110
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