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Dual targeting of the Akt/mTOR signaling pathway inhibits castration-resistant prostate cancer in a genetically engineered mouse model

While the prognosis for clinically localized prostate cancer is now favorable, there are still no curative treatments for castration-resistant prostate cancer and, therefore, remains fatal. In this study, we investigate a new therapeutic approach for treatment of castration-resistant prostate cancer...

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Detalhes bibliográficos
Main Authors: Floc'h, Nicolas, Kinkade, Carolyn Waugh, Kobayashi, Takashi, Aytes, Alvaro, Lefebvre, Celine, Mitrofanova, Antonina, Cardiff, Robert D., Califano, Andrea, Shen, Michael M., Abate-Shen, Cory
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432676/
https://ncbi.nlm.nih.gov/pubmed/22815528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-0283
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