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Targeting the ubiquitin–proteasome system for cancer therapy

INTRODUCTION: The ubiquitin–proteasome system (UPS) degrades 80 – 90% of intracellular proteins. Cancer cells take advantage of the UPS for their increased growth and decreased apoptotic cell death. Thus, the components that make up the UPS represent a diverse group of potential anti-cancer targets....

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Autors principals: Shen, Min, Schmitt, Sara, Buac, Daniela, Dou, Q Ping
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773690/
https://ncbi.nlm.nih.gov/pubmed/23822887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2013.815728
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