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Targeting the ubiquitin–proteasome system for cancer therapy
INTRODUCTION: The ubiquitin–proteasome system (UPS) degrades 80 – 90% of intracellular proteins. Cancer cells take advantage of the UPS for their increased growth and decreased apoptotic cell death. Thus, the components that make up the UPS represent a diverse group of potential anti-cancer targets....
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3773690/ https://ncbi.nlm.nih.gov/pubmed/23822887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2013.815728 |
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