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The Ubiquitin-Proteasome System as a Prospective Molecular Target for Cancer Treatment and Prevention

Proteasomes are large multicatalytic proteinase complexes located in the cytosol and the nucleus of eukaryotic cells. The ubiquitin-proteasome system is responsible for the degradation of most intracellular proteins and therefore plays an essential regulatory role in critical cellular processes incl...

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Detalhes bibliográficos
Main Authors: Chen, Di, Dou, Q. Ping
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306609/
https://ncbi.nlm.nih.gov/pubmed/20491623
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