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Rhodium-catalyzed enantioselective cyclopropanation of electron deficient alkenes

The rhodium-catalyzed reaction of electron-deficient alkenes with substituted aryldiazoacetates and vinyldiazoacetates results in highly stereoselective cyclopropanations. With adamantylglycine derived catalyst Rh(2)(S-TCPTAD)(4), high asymmetric induction (up to 98% ee) can be obtained with a range...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wang, Hengbin, Guptill, David M., Alvarez, Adrian Varela, Musaev, Djamaladdin G., Davies, Huw M. L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773518/
https://ncbi.nlm.nih.gov/pubmed/24049630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C3SC50425E
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