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Sequence-independent processing site of the C-terminal domain (CTD) influences maturation of the RgpB protease from Porphyromonas gingivalis

The Gram-negative periodontal pathogen Porphyromonas gingivalis produces a family of outer membrane-anchored proteases, the gingipains, shown to play an essential role in virulence of the organism. The C-terminal domain (CTD) of gingipains and other secreted proteins is known to be the targeting sig...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhou, Xiao-Yan, Gao, Jin-Long, Hunter, Neil, Potempa, Jan, Nguyen, Ky-Anh
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773331/
https://ncbi.nlm.nih.gov/pubmed/23869473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12319
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