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Sequence-independent processing site of the C-terminal domain (CTD) influences maturation of the RgpB protease from Porphyromonas gingivalis

The Gram-negative periodontal pathogen Porphyromonas gingivalis produces a family of outer membrane-anchored proteases, the gingipains, shown to play an essential role in virulence of the organism. The C-terminal domain (CTD) of gingipains and other secreted proteins is known to be the targeting sig...

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Detalhes bibliográficos
Main Authors: Zhou, Xiao-Yan, Gao, Jin-Long, Hunter, Neil, Potempa, Jan, Nguyen, Ky-Anh
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773331/
https://ncbi.nlm.nih.gov/pubmed/23869473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12319
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