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Specific inhibition of PI3K p110δ inhibits CSF-1-induced macrophage spreading and invasive capacity

Colony stimulating factor-1 (CSF-1) stimulates mononuclear phagocytic cell survival, growth and differentiation into macrophages through activation and autophosphorylation of the CSF-1 receptor (CSF-1R). We have previously demonstrated that CSF-1-induced phosphorylation of Y721 in the receptor kinas...

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Detalhes bibliográficos
Main Authors: Mouchemore, Kellie A., Sampaio, Natalia G., Murrey, Michael W., Stanley, E. Richard, Lannutti, Brian J., Pixley, Fiona J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773002/
https://ncbi.nlm.nih.gov/pubmed/23648053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.12316
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