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Neuroactive Steroids for the Treatment of Status Epilepticus

Benzodiazepines are the current first-line standard-of-care treatment for status epilepticus but fail to terminate seizures in about one-third of cases. Synaptic GABA(A) receptors, which mediate phasic inhibition in central circuits, are the molecular target of benzodiazepines. As status epilepticus...

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Bibliografske podrobnosti
Main Authors: Rogawski, Michael A., Loya, Carlos M., Reddy, Kiran, Zolkowska, Dorota, Lossin, Christoph
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772544/
https://ncbi.nlm.nih.gov/pubmed/24001085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.12289
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