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Modelling of human Wiskott–Aldrich syndrome protein mutants in zebrafish larvae using in vivo live imaging
Wiskott–Aldrich syndrome (WAS) and X-linked neutropenia (XLN) are immunodeficiencies in which the function of several haematopoietic cell lineages is perturbed as a result of mutations in the actin regulator WASp. From in vitro cell biology experiments, and biochemical and structural approaches, we...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Company of Biologists
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3772384/ https://ncbi.nlm.nih.gov/pubmed/23868979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.128728 |
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