ロード中...

Mitochondrial DNA Ligase Is Dispensable for the Viability of Cultured Cells but Essential for mtDNA Maintenance

Multiple lines of evidence support the notion that DNA ligase III (LIG3), the only DNA ligase found in mitochondria, is essential for viability in both whole organisms and in cultured cells. Previous attempts to generate cells devoid of mitochondrial DNA ligase failed. Here, we report, for the first...

詳細記述

保存先:
書誌詳細
主要な著者: Shokolenko, Inna N., Fayzulin, Rafik Z., Katyal, Sachin, McKinnon, Peter J., Wilson, Glenn L., Alexeyev, Mikhail F.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772206/
https://ncbi.nlm.nih.gov/pubmed/23884459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.472977
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!