A Link between ORC-Origin Binding Mechanisms and Origin Activation Time Revealed in Budding Yeast

Eukaryotic DNA replication origins are selected in G1-phase when the origin recognition complex (ORC) binds chromosomal positions and triggers molecular events culminating in the initiation of DNA replication (a.k.a. origin firing) during S-phase. Each chromosome uses multiple origins for its duplic...

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Detalhes bibliográficos
Main Authors: Hoggard, Timothy, Shor, Erika, Müller, Carolin A., Nieduszynski, Conrad A., Fox, Catherine A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772097/
https://ncbi.nlm.nih.gov/pubmed/24068963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003798
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