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The spatial arrangement of ORC binding modules determines the functionality of replication origins in budding yeast

In the quest to define autonomously replicating sequences (ARSs) in eukaryotic cells, an ARS consensus sequence (ACS) has emerged for budding yeast. This ACS is recognized by the replication initiator, the origin recognition complex (ORC). However, not every match to the ACS constitutes a replicatio...

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Detalhes bibliográficos
Main Authors: Bolon, Yung-Tsi, Bielinsky, Anja-Katrin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635292/
https://ncbi.nlm.nih.gov/pubmed/16984967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl661
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