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High-resolution analysis of four efficient yeast replication origins reveals new insights into the ORC and putative MCM binding elements

In budding yeast, the eukaryotic initiator protein ORC (origin recognition complex) binds to a bipartite sequence consisting of an 11 bp ACS element and an adjacent B1 element. However, the genome contains many more matches to this consensus than actually bind ORC or function as origins in vivo. Alt...

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Detalhes bibliográficos
Main Authors: Chang, FuJung, May, Caitlin D., Hoggard, Timothy, Miller, Jeremy, Fox, Catherine A., Weinreich, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159467/
https://ncbi.nlm.nih.gov/pubmed/21558171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr301
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