A Neutralizing Monoclonal Antibody Targeting the Acid-Sensitive Region in Chikungunya Virus E2 Protects from Disease

The mosquito-borne alphavirus, chikungunya virus (CHIKV), has recently reemerged, producing the largest epidemic ever recorded for this virus, with up to 6.5 million cases of acute and chronic rheumatic disease. There are currently no licensed vaccines for CHIKV and current anti-inflammatory drug tr...

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Detalhes bibliográficos
Main Authors: Selvarajah, Suganya, Sexton, Nicole R., Kahle, Kristen M., Fong, Rachel H., Mattia, Kimberly-Anne, Gardner, Joy, Lu, Kai, Liss, Nathan M., Salvador, Beatriz, Tucker, David F., Barnes, Trevor, Mabila, Manu, Zhou, Xiangdong, Rossini, Giada, Rucker, Joseph B., Sanders, David Avram, Suhrbier, Andreas, Sambri, Vittorio, Michault, Alain, Muench, Marcus O., Doranz, Benjamin J., Simmons, Graham
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772074/
https://ncbi.nlm.nih.gov/pubmed/24069479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002423
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