Exposure of Epitope Residues on the Outer Face of the Chikungunya Virus Envelope Trimer Determines Antibody Neutralizing Efficacy

Chikungunya virus (CHIKV) is a reemerging alphavirus that causes a debilitating arthritic disease and infects millions of people and for which no specific treatment is available. Like many alphaviruses, the structural targets on CHIKV that elicit a protective humoral immune response in humans are po...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Fong, Rachel H., Banik, Soma S. R., Mattia, Kimberly, Barnes, Trevor, Tucker, David, Liss, Nathan, Lu, Kai, Selvarajah, Suganya, Srinivasan, Surabhi, Mabila, Manu, Miller, Adam, Muench, Marcus O., Michault, Alain, Rucker, Joseph B., Paes, Cheryl, Simmons, Graham, Kahle, Kristen M., Doranz, Benjamin J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249124/
https://ncbi.nlm.nih.gov/pubmed/25275138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01943-14
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