Exposure of Epitope Residues on the Outer Face of the Chikungunya Virus Envelope Trimer Determines Antibody Neutralizing Efficacy

Chikungunya virus (CHIKV) is a reemerging alphavirus that causes a debilitating arthritic disease and infects millions of people and for which no specific treatment is available. Like many alphaviruses, the structural targets on CHIKV that elicit a protective humoral immune response in humans are po...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Fong, Rachel H., Banik, Soma S. R., Mattia, Kimberly, Barnes, Trevor, Tucker, David, Liss, Nathan, Lu, Kai, Selvarajah, Suganya, Srinivasan, Surabhi, Mabila, Manu, Miller, Adam, Muench, Marcus O., Michault, Alain, Rucker, Joseph B., Paes, Cheryl, Simmons, Graham, Kahle, Kristen M., Doranz, Benjamin J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
Soggetti:
Vaccines and Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249124/
https://ncbi.nlm.nih.gov/pubmed/25275138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01943-14
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