Mechanism of Binding to Ebola Virus Glycoprotein by the ZMapp, ZMAb, and MB-003 Cocktail Antibodies

Cocktails of monoclonal antibodies (MAbs) that target the surface glycoprotein (GP) of Ebola virus (EBOV) are effective in nonhuman primate models and have been used under emergency compassionate-treatment protocols in human patients. However, the amino acids that form the detailed binding epitopes...

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Detaylı Bibliyografya
Yayımlandı:J Virol
Asıl Yazarlar: Davidson, Edgar, Bryan, Christopher, Fong, Rachel H., Barnes, Trevor, Pfaff, Jennifer M., Mabila, Manu, Rucker, Joseph B., Doranz, Benjamin J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2015
Konular:
Vaccines and Antiviral Agents
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621129/
https://ncbi.nlm.nih.gov/pubmed/26311869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01490-15
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