Protecting a transgene expression from the HAC-based vector by different chromatin insulators

Human artificial chromosomes (HACs) are vectors that offer advantages of capacity and stability for gene delivery and expression. Several studies have even demonstrated their use for gene complementation in gene-deficient recipient cell lines and animal transgenesis. Recently, we constructed an adva...

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Autors principals: Lee, Nicholas CO, Kononenko, Artem V., Lee, Hee-Sheung, Tolkunova, Elena N., Liskovykh, Mikhail A., Masumoto, Hiroshi, Earnshaw, William C., Tomilin, Alexey N., Larionov, Vladimir, Kouprina, Natalay
Format: Artigo
Idioma:Inglês
Publicat: Springer Basel 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3771377/
https://ncbi.nlm.nih.gov/pubmed/23677492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-013-1362-9
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