Biocatalytic Synthesis of Pikromycin, Methymycin, Neomethymycin, Novamethymycin, and Ketomethymycin

A biocatalytic platform that employs the final two monomodular type I polyketide synthases (PKS) of the pikromycin pathway in vitro followed by direct appendage of D-desosamine and final C-H oxidation(s) in vivo was developed and applied toward the synthesis of a suite of 12-and 14-membered ring mac...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hansen, Douglas A., Rath, Christopher M., Eisman, Eli B., Narayan, Alison R. H., Kittendorf, Jeffrey D., Mortison, Jonathan D., Yoon°, Yeo Joon, Sherman, David H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3771335/
https://ncbi.nlm.nih.gov/pubmed/23866020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja404134f
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg