The Pattern of Cortical Dysfunction in a Mouse Model of a Schizophrenia-Related Microdeletion

We used a mouse model of the schizophrenia-predisposing 22q11.2 microdeletion to evaluate how this genetic lesion affects cortical neural circuits at the synaptic, cellular, and molecular levels. Guided by cognitive deficits, we demonstrated that mutant mice display robust deficits in high-frequency...

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Main Authors: Fénelon, Karine, Xu, Bin, Lai, Cora S., Mukai, Jun, Markx, Sander, Stark, Kimberly L., Hsu, Pei-Ken, Gan, Wen-Biao, Fischbach, Gerald D., MacDermott, Amy B., Karayiorgou, Maria, Gogos, Joseph A.
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2013
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Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3771024/
https://ncbi.nlm.nih.gov/pubmed/24027283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1611-13.2013
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